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Study details
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A Study of CBX-12 in Subjects With Platinum Resistant or Refractory Ovarian Cancer

Cybrexa Therapeutics
NCT IDNCT06315491ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

40

Study length

about 1.1 years

Ages

18+

Sex

Female only

Locations

17 sites in AZ, CA, CT +10

What this study is about

This trial is testing a treatment called CBX-12 in women with ovarian cancer that has not responded to platinum chemotherapy. The goal is to see if this treatment is safe and effective.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take CBX-12

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Percentage of Subjects With Complete Response (CR) or Partial Response (PR) [Objective Response Rate (ORR)]

Secondary: Incidence of Subjects With Treatment Emergent Adverse Events (TEAEs), Median Duration of Response (DoR), Plasma levels of CBX-12 (Cmax), Plasma levels of CBX-12 (Tmax), Plasma levels of Exatecan (Cmax), Plasma levels of Exatecan (Tmax), Progression-Free Survival (PFS)

Body systems

Oncology