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Study details
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A Study to Assess Adverse Events, and How Intravenously (IV) Infused ABBV-969 Moves Through the Bodies of Adult Participants With Metastatic Castration-Resistant Prostate Cancer

AbbVie
NCT IDNCT06318273ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

140

Study length

about 3.2 years

Ages

18+

Sex

Male only

Locations

9 sites in CA, CT, FL +5

What this study is about

This trial is testing a new medication called ABBV-969 in people with advanced prostate cancer that has not responded to other treatments. The goal is to see if this medication is safe and how it works in the body. Participants will receive ABBV-969 through an IV infusion at different doses, and they will be monitored closely for any side effects.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take ABBV-969

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug routes

intravenous

Endpoints

Primary: Percentage of Participants With Adverse Events (AEs)

Secondary: Area Under the Plasma/Serum Concentration Versus Time Curve (AUC) of ABBV-969, Maximum Observed Plasma Concentration (Cmax) of ABBV-969, Terminal Phase Elimination Half-Life (t1/2) of ABBV-969, Time to Maximum Observed Concentration (Tmax) of ABBV-969

Body systems

Oncology