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Study details
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Risk Stratified De-escalated Hormone Therapy With Radiation Therapy for the Treatment of Prostate Cancer

Mayo Clinic
NCT IDNCT06369610ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

110

Study length

about 3 years

Ages

18+

Locations

1 site in AZ

What this study is about

This trial is testing whether a less aggressive approach to hormone therapy, combined with radiation, can be as effective as standard treatment for prostate cancer. The goal is to determine if reducing the number of hormone treatments (ADT) while still using radiation can provide similar benefits to more intensive ADT regimens in patients whose risk factors suggest they could benefit from a less aggressive strategy.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Questionnaire Administration
  • 2.Receive Gonadotropin-releasing Hormone Analog
  • 3.Receive Radiation Therapy
  • +3 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

Antineoplastic Agent [TC] (Cytochrome P450 17A1 Inhibitors), gonadorelin

Drug routes

oral

Procedures

diagnostic, imaging, radiation