Pain Control and Quality of Recovery After Intravenous Methadone Versus Intrathecal Morphine in Major Abdominal Surgery
EARLY_PHASE1
40
about 1.8 years
18–75
1 site in VA
What this study is about
This trial is testing whether intravenous methadone is as good as intrathecal morphine for managing pain after major abdominal surgery. The goal is to see if IV methadone can help reduce the need for opioids, improve recovery, and lower hospital stays compared to IT morphine.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Methadone
- 2.Take Morphine
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
methadone (Long-acting opioid; prevents withdrawal and reduces craving), morphine (Opioid; binds mu-opioid receptors to relieve pain)
infusion
Primary: Numeric Rating Scale pain scores (NRS)
Secondary: McGill Pain questionnaire score, Numeric Rating Pain Score (NRS)