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Study details
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Autologous CD22 CAR T Cells Following Commercial CD19 CAR T Cells in B Cell Malignancies

Stanford University
NCT IDNCT06408194ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

20

Study length

about 1.6 years

Ages

1–25

Locations

1 site in CA

What this study is about

This trial is testing the safety and how well a new treatment, autologous CD22 CAR T cells, works when given after a commercial CAR T cell therapy called Tisagenlecleucel. The goal is to find out if this new treatment can be safely used in children and young adults with relapsed or refractory B-cell leukemia.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive CD22CART infusion
  • 2.Take Tisagenlecleucel

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVInjection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

tisagenlecleucel (CAR T-cell therapy targeting CD19 on leukemia cells)

Drug routes

infusion

Body systems

Oncology