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Study details
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Dose Optimization of MDMA-Assisted Therapy for PTSD

Bronx VA Medical Center
NCT IDNCT06418178ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

60

Study length

about 4.4 years

Ages

18+

Locations

1 site in NY

What this study is about

This trial is testing different doses of MDMA-assisted therapy to find the best number of treatment cycles (MDMA sessions and integration sessions) for U.S. veterans with PTSD. Participants will complete one to five cycles of MDMA-AT.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Participate in Psychotherapy
  • 2.Take Midomafetamine

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: PTSD Checklist for DSM-5 (PCL-5)

Secondary: Clinician-Administered PTSD Scale for DSM-5 (CAPS-5)

Body systems

Psychiatry / Mental Health