Impact of Cognitive Behavioral Therapy on PTSD-CVD Link
30
about 3 years
18–65
1 site in MA
What this study is about
Researchers are testing whether cognitive processing therapy (CPT), a type of behavioral treatment, can reduce the risk of cardiovascular disease (CVD) in people with posttraumatic stress disorder (PTSD). The trial will also examine how CPT affects inflammation and autonomic function, and if these changes are linked to alterations in stress-related neural activity.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Participate in Cognitive processing therapy
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Primary: Heart rate variability
Secondary: Axonal integrity of resting neural connections between brain centers using MRI, Blood pressure, Heart rate, MRI based arterial plaque components (such as necrotic tissue, loose connective tissue, and hemorrhage), MRI based arterial wall thickness, MRI based brain activation (via measuring blood flow in important neural centers at rest and with an emotional task using functional MRI), MRI based brain connectivity (by measuring changes in blood flow across networks of neural centers at rest and with an emotional task), MRI based brain structure assessments of volume and density
Psychiatry / Mental Health