ACTION Trial
Phase 1/2
240
about 4.6 years
18+
1 site in SC
What this study is about
Researchers are testing whether adding buprenorphine, CBT, and TMS to long-term opioid therapy can improve outcomes for people with chronic pain. The trial will evaluate three interventions: a low dose of buprenorphine without withdrawal, a brief Cognitive Behavioral Intervention (CBI), and accelerated rTMS over the left dorsolateral prefrontal cortex. Participants will be followed for 1692 days.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Buprenorphine Patch
- 2.Take Placebo
- 3.Use Sham Transcranial Magnetic Stimulation (TMS)
- +1 more
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
buprenorphine
sublingual, transdermal
Primary: Buprenorphine Tolerability, Pain Severity -with Buprenorphine Patch
Secondary: Quality of Life -with Buprenorphine Patch
therapeutic
Psychiatry / Mental Health