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Study details
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Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

Ohio State University
NCT IDNCT06468202ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

10,742

Study length

about 5.3 years

Ages

14–35

Sex

Female only

Locations

16 sites in AL, CA, IL +11

What this study is about

This trial is testing whether 162 mg of aspirin daily is better than 81 mg of aspirin daily in preventing hypertensive disorders of pregnancy. The goal is to understand factors that affect how well women take the aspirin and use this information to improve care for pregnant women at risk.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Aspirin 162 mg
  • 2.Take Aspirin 81 mg

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

acetylsalicylic acid

Drug routes

oral (Delayed Release Oral Tablet)

Body systems

Reproductive Health, Cardiology / Heart