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Study details
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Invert-Prospective Phase II Randomized Trial of Involved Nodal Versus Elective Neck RadioTherapy

University of Texas Southwestern Medical Center
NCT IDNCT06477692ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

80

Study length

about 3.6 years

Ages

18–99

Locations

1 site in TX

What this study is about

This trial is testing whether targeting specific, potentially cancerous lymph nodes (INRT) is better than treating all lymph nodes (ENI) for head and neck cancer. The goal is to reduce side effects from radiation treatment by focusing on the areas most likely to contain cancer cells.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive ENI
  • 2.Receive INRT
  • 3.Take ENI using IMRT with or without chemotherapy

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: MDADI Quality of Life composite score

Body systems

Oncology