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Study details
Enrolling now

Isatuximab, Dexamethasone, and Lenalidomide for Frail Multiple Myeloma Patients

University of Utah
NCT IDNCT06517017ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

40

Study length

about 2.1 years

Ages

18+

Locations

1 site in UT

What this study is about

This trial is testing a go-slow approach to treating multiple myeloma in very frail patients. The treatment starts with Isatuximab and dexamethasone, then gradually introduces lenalidomide. The goal is to see if this gentler start improves how well people stick to their treatment plan and improves their quality of life.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Isatuximab

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

isatuximab

Endpoints

Secondary: Change in quality of life as per the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30 domain, Frequency of adverse events (AEs) and serious adverse events (SAEs) characterized by duration, Frequency of adverse events (AEs) and serious adverse events (SAEs) characterized by relationship to study treatment, Frequency of adverse events (AEs) and serious adverse events (SAEs) characterized by seriousness, Frequency of adverse events (AEs) and serious adverse events (SAEs) characterized by severity (as defined by the NIH CTCAE, version 5.0), Frequency of adverse events (AEs) and serious adverse events (SAEs) characterized by type, Overall survival (OS)

Body systems

Oncology