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Study details
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A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors

Alterome Therapeutics, Inc.
NCT IDNCT06533059ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

110

Study length

about 3.4 years

Ages

18+

Locations

18 sites in CA, CO, FL +9

What this study is about

This trial is testing a treatment called ALTA2618 for adults with advanced solid tumors that have the AKT1 E17K mutation. The goal is to learn about how safe and effective ALTA2618 is in these patients.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take ALTA2618

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Adverse Events, Dose Limiting Toxicities

Secondary: Duration of Response (DOR), Maximum Observed Plasma Concentration (Cmax), Overall Response Rate (ORR), Overall Survival (OS), Progression-Free Survival (PFS), Terminal Half-Life (t1/2), Time to Reach Maximum Observed Plasma Concentration (Tmax)

Body systems

Oncology