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Study details
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Study to Assess Tezampanel for Opioid Withdrawal Syndrome

Proniras Corporation
NCT IDNCT06538558ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

40

Study length

about 1.1 years

Ages

18–65

Locations

1 site in IN

What this study is about

This trial is testing whether Tezampanel (TZP) can help with opioid withdrawal syndrome in people who have opioid use disorder. Participants will receive either TZP or a placebo daily for 7 days during their stay at the research center.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Placebo
  • 2.Take Tezampanel

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: To evaluate systemic tolerability and safety of intravenous tezampanel administration.

Secondary: To characterize Area Under the Curve (AUC) concentration of tezampanel, To characterize Cmax (maximum concentration) of tezampanel

Body systems

Psychiatry / Mental Health