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Study details
Enrolling now

Combined THC and CBD for OUD and Chronic Pain

Yale University
NCT IDNCT06544291ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

147

Study length

about 3.3 years

Ages

18–65

Locations

1 site in CT

What this study is about

This trial is testing a treatment with combined THC and CBD to help people with opioid use disorder (OUD) and chronic pain. The goal is to see if this treatment reduces both pain and cravings for opioids.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take CBD 300mg
  • 2.Take CBD 600mg
  • 3.Take Placebo 0mg

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

cannabinoid

Endpoints

Primary: Primary Outcome Variable #1: Pain Sensitivity

Secondary: Secondary Outcome Variable #3a: Monitor adverse events from the study medications (SAFTEE), Secondary Outcome Variable #3b: Monitor adverse events from the study medications (Cardiovascular)

Body systems

Psychiatry / Mental Health