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Study details
Enrolling now

Biology-Guided Radiation Therapy for Bone Metastases

City of Hope Medical Center
NCT IDNCT06549478ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

24

Study length

about 2.5 years

Ages

18+

Locations

1 site in CA

What this study is about

This trial is testing the safety and effectiveness of a single dose of biology-guided radiation therapy (BgRT) in treating painful bone metastases. BgRT uses a signal from positron emission tomography to guide external beam radiation therapy, potentially offering safer and more effective pain relief compared to traditional methods.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Questionnaire Administration
  • 2.Receive Image Guided Radiation Therapy
  • 3.Undergo Computed Tomography
  • +1 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Incidence of adverse events, Pain response

Secondary: Patient-reported health related quality of life (QOL), Radiographic evidence of disease progression

Procedures

imaging, radiation