Skip to content
Study details
Enrolling now

Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy for Palliative Head and Neck Cancer Treatment (PULS-Pal)

Jonsson Comprehensive Cancer Center
NCT IDNCT06572423ClinicalTrials.gov data as of Apr 2026
Target enrollment

43

Study length

about 5.1 years

Ages

18+

Locations

1 site in CA

What this study is about

This trial is testing personalized ultra fractionated stereotactic adaptive radiotherapy (PULSAR) together with HyperArc radiation treatment planning technology to see if it helps control tumors in people with head and neck cancer who can't have standard treatments. Researchers want to determine if using HyperArc and PULSAR will deliver higher doses of radiation, potentially leading to better tumor control with fewer side effects than smaller routine doses.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Best Practice
  • 2.Participate in Functional Assessment of Cancer Therapy-Head & Neck
  • 3.Participate in University of Washington Quality of Life Scale, Version 4
  • +3 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Time to progression of the treated tumor target

Secondary: Disease progression free survival (PFS), Grade 3 or higher treatment-related toxicity, Incidence of adverse events (AE), Longitudinal patient reported outcomes on the Functional Assessment of Cancer Therapy - Head and Neck (FACT-H&N) Questionnaire, Longitudinal patient reported outcomes on the University of Washington Quality of Life (UW-QoL) Questionnaire, Overall survival (OS)

Procedures

imaging, diagnostic, radiation

Body systems

Oncology