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Study details
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Hyperbaric Oxygen Treatment for Veterans With Traumatic Brain Injury

University of South Florida
NCT IDNCT06581003ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

420

Study length

about 4.9 years

Ages

18–75

Locations

1 site in FL

What this study is about

Researchers are testing whether hyperbaric oxygen therapy (HBOT) can help improve symptoms in veterans and active military with mild to moderate traumatic brain injury. The trial will compare HBOT to a placebo condition, where participants breathe normal air. Participants will receive 40 sessions of either HBOT or the placebo over 12 weeks.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Oxygen 21 %
  • 2.Take Oxygen 99.7 %

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

oxygen

Endpoints

Primary: Change from Baseline in the Neurobehavioral Symptoms at 2 weeks Post Intervention

Secondary: Change from Baseline in post traumatic stress disorder symptoms at 2 weeks post intervention