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Study details
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Intravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell Disease

Suvankar Majumdar
NCT IDNCT06635902ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

99

Study length

about 4.3 years

Ages

4–21

Locations

1 site in DC

What this study is about

Researchers are testing if intravenous L-citrulline helps treat acute pain episodes in people with sickle cell disease. The trial also aims to learn about the safety of this treatment and how it affects participants.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Placebo
  • 2.Take L-citrulline

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug routes

oral (Oral Capsule)

Endpoints

Secondary: Opioid consumption, Pain scores, Safety