Study details
Enrolling now
Combined Guanfacine and Mindfulness Meditation as an Adjunct to Buprenorphine Maintenance in Opioid Use Disorder
Rutgers, The State University of New Jersey
NCT IDNCT06642181ClinicalTrials.gov data as of Apr 2026
Phase
Phase 1
Target enrollment
224
Study length
about 1.2 years
Ages
18–55
Locations
1 site in NJ
What this study is about
This trial is testing whether combining guanfacine with mindfulness meditation helps people who are already taking buprenorphine for opioid use disorder stay sober longer. This treatment involves taking a medication called guanfacine and participating in a mindfulness program.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Participate in Mindfulness Oriented Recovery Enhancement (MORE)
- 2.Take Guanfacine pharmacotherapy
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Oral
How treatment is administered
Treatment Assignment
Randomized & Blinded
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Drug classes
CARDIOVASCULAR SYSTEM
Drug routes
oral (Oral Tablet)
Endpoints
Primary: Anxiety, Heart Rate, Mood
Body systems
Psychiatry / Mental Health