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Study details
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A Study of Raludotatug Deruxtecan in Participants With Advanced/Metastatic Solid Tumors (REJOICE-PanTumor01)

Daiichi Sankyo
NCT IDNCT06660654ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

200

Study length

about 2.7 years

Ages

18+

Locations

8 sites in GA, MI, NJ +3

What this study is about

This trial is testing a treatment called raludotatug deruxtecan (R-DXd) for people with advanced or metastatic solid tumors. The goal is to see if R-DXd can help improve the lives of those who have these types of cancers.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Raludotatug deruxtecan

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Disease Control Rate (DCR) as Assessed by the Investigator (ccRCC Cohort Only), Number of Participants Reporting Treatment-emergent Adverse Events (TEAEs), Serious Adverse Events (SAEs), and Adverse Events of Special Interest (AESIs) (All Cohorts), Objective Response Rate as Assessed by the Investigator (All Cohorts Except ccRCC)

Secondary: Disease Control Rate (DCR) as Assessed by the Investigator (All Cohorts Except ccRCC Cohort), Duration of Response (DoR) as Assessed by the Investigator, Objective Response Rate as Assessed by the Investigator (ccRCC Cohort Only), Pharmacokinetic Parameter Maximum Concentration (Cmax) of R-DXd, Progression-free Survival (PFS) as Assessed by the Investigator

Body systems

Oncology