A Study of JNJ-89402638 for Metastatic Colorectal Cancer
Phase 1
170
about 3.8 years
18+
5 sites in CO, FL, IN +2
What this study is about
This trial is testing a treatment called JNJ-89402638 in people with advanced colorectal cancer that cannot be surgically removed. The goal is to find the best dose of this medication and see if it's safe at that dose.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take JNJ-89402638
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Assignment is predetermined by the study protocol.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
bevacizumab
infusion
Primary: Part 1 and Part 2: Number of Participants with Adverse Events (AEs) by Severity, Part 1: Number of Participants with Dose-Limiting Toxicity (DLT)
Secondary: Part 1 and Part 2: Area Under the Serum Concentration-time Curve (AUC) of JNJ-89402638, Part 1 and Part 2: Complete Response (CR), Part 1 and Part 2: Duration of Response (DOR), Part 1 and Part 2: Maximum Serum Concentration (Cmax) of JNJ-89402638, Part 1 and Part 2: Overall Response (OR), Part 1 and Part 2: Time to Reach Maximum Observed Serum Concentration (Tmax) of JNJ-89402638
Oncology