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Study details
Enrolling now

Brodalumab for Immune-Related Side Effects

Brian Henick, MD
NCT IDNCT06673329ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

11

Study length

about 1.7 years

Ages

18+

Locations

1 site in NY

What this study is about

This trial is testing the safety and effectiveness of using brodalumab to manage immune-related side effects in people with cancer who are receiving immunotherapy. Brodalumab, which is used to treat autoimmune diseases, may help control these side effects by targeting similar immune system activation.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive CT scan
  • 2.Take Brodalumab

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

brodalumab

Endpoints

Primary: Number of Adverse Events, Percentage of primary Immune-Related Adverse Event (irAE) severity decreased

Secondary: Mean Time to Complete Resolution of irAE Symptoms, Overall Survival (OS), Progression-free survival (PFS)

Procedures

imaging

Body systems

Oncology