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Study details
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Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia

Boston University
NCT IDNCT06757075ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

75

Study length

about 12 months

Ages

4–6

Locations

1 site in MA

What this study is about

This trial is testing whether different pain medications help reduce discomfort after dental work under anesthesia in young children. It compares ibuprofen alone, alternating ibuprofen and acetaminophen, and combined ibuprofen and acetaminophen to see which approach works best for managing postoperative pain.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Acetominophen
  • 2.Take Ibuprofen

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

paracetamol (Reduces fever and pain (mechanism not fully understood)), ibuprofen

Drug routes

oral

Endpoints

Primary: Pain assessment based on the FLACC