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Study details
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A Study of LY4006896

Eli Lilly and Company
NCT IDNCT06809400ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

127

Study length

about 3 years

Ages

30–85

Locations

11 sites in CA, FL, MI +2

What this study is about

This trial is testing a treatment called LY4006896 in people with Parkinson's disease and healthy adults. The goal is to see if this treatment is safe and how it works in the body.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take LY4006896
  • 2.Take Placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Number of Participants with One or More SAEs Part B, Number of Participants with One or More Serious Adverse Event(s) (SAEs) Part A, Number of Participants with One or More TEAEs Part B, Number of Participants with One or More Treatment-Emergent Adverse Events (TEAEs) Part A

Secondary: PK: AUC of LY4006896 ARC-Associated Antisense Part B, PK: Area Under the Concentration versus Time Curve (AUC) of LY4006896 ARC-Associated Antisense Part A, PK: Cmax of LY4006896 ARC-Associated Antisense Part B, Pharmacokinetics (PK): Maximum Concentration (Cmax) of LY4006896 ARC-Associated Antisense Part A

Body systems

Neurology