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Study details
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Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia Survivors

St. Jude Children's Research Hospital
NCT IDNCT06819475ClinicalTrials.gov data as of Apr 2026
Target enrollment

60

Study length

about 2.7 years

Ages

18+

Locations

1 site in TN

What this study is about

This trial is testing how skeletal muscle mitochondria function in people who have survived acute lymphoblastic leukemia (ALL). It involves imaging techniques and blood tests to compare muscle health between ALL survivors and a control group. The goal is to understand the relationship between cancer treatment, muscle weakness, and mitochondrial activity.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Magnetic Resonance Spectroscopy
  • 2.Peripheral blood sample
  • 3.Physical function assessment
  • +3 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: To explore feasibility of CrCEST MRI to measure OXPHOS capacity, To explore feasibility of Fat Fraction MRI to measure OXPHOS capacity, To explore feasibility of MRI/MRS to measure OXPHOS capacity, To explore feasibility of Muscle Ultrasound to measure OXPHOS capacity

Procedures

imaging

Body systems

Oncology