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Study details
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A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects

Zona Health, Inc
NCT IDNCT06843577ClinicalTrials.gov data as of Apr 2026
Target enrollment

160

Study length

about 2.2 years

Ages

22+

Locations

5 sites in CA, FL, IL +2

What this study is about

Researchers are testing whether using a handgrip device or relaxing music can help lower blood pressure. The trial will involve adults with high blood pressure who are not already taking medication for their condition. Participants will use either the handgrip device or listen to relaxing music, and some will also monitor their blood pressure at home.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Relaxing Music App
  • 2.Use Zona Plus Device

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Compare the change from baseline in mean seated cuff systolic blood pressure (SBP) after 10 weeks of treatment between patients randomized to the Zona Plus device and the patients in the control group.

Secondary: To compare the change from baseline in seated cuff diastolic blood pressure (DBP) after 10 weeks of treatment between patients randomized to the Zona Plus device and the patients in the control group.

Body systems

Cardiology / Heart