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Study details
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A Research Study to Evaluate the Safety of NNC4004-0002 When Given to Participants With Asymptomatic Hyperuricemia

Novo Nordisk A/S
NCT IDNCT06859073ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

60

Study length

about 1.5 years

Ages

35–75

Locations

2 sites in CA, MD

What this study is about

Researchers are testing a new medicine called NNC4004-0002 to see if it's safe when given to people with high uric acid levels who don't have any symptoms. The trial will involve giving participants either the medicine or a placebo (a harmless substance) by injection under their skin. Participants will be asked to visit the clinic for several appointments and may need to stay overnight at the clinic for one of these visits.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take NNC4004-0002
  • 2.Take Placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Number of Treatment-emergent adverse event (TEAEs)

Secondary: AUC(0-72): The area under the NNC4004-0002 plasma concentration-time curve from time zero to the 72 hours after a single dose, Cmax: The maximum concentration of NNC4004-0002 in plasma, Renal clearance, tmax: The time from dose administration to the maximum plasma concentration of NNC4004-0002