Study details
Enrolling now
PULSO Trial: Pulsed Low-Dose-Rate (PLDR) Radiation Chemoradiation (CRT) vs. Standard CRT for Esophageal Cancer
Medical College of Wisconsin
NCT IDNCT06906887ClinicalTrials.gov data as of Apr 2026
Phase
Phase 2
Target enrollment
50
Study length
about 7 years
Ages
18+
Locations
1 site in WI
What this study is about
Researchers are testing whether pulsed low-dose-rate radiation, as compared to standard radiation, reduces the risk of clinically significant esophagitis during and after chemoradiation in people with esophageal cancer. The trial will involve chemotherapy, surgery, and either pulsed low-dose-rate radiation or standard radiation.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Receive Conventional Radiation
- 2.Receive Pulsed Low-Dose-Rate (PLDR) Radiation
- 3.Take Chemotherapy
- +2 more
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Injection / IV
How treatment is administered
Treatment Assignment
Randomized (Open Label)
You are randomly assigned, but you will know your treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Drug routes
infusion
Procedures
radiation, surgery
Body systems
Oncology