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Study details
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CTX112 Trial

CRISPR Therapeutics
NCT IDNCT06925542ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

80

Study length

about 6.8 years

Ages

18–70

Locations

6 sites in CA, IA, IL +3

What this study is about

Researchers are testing the safety and preliminary effectiveness of CTX112 in adults with autoimmune diseases like lupus, scleroderma, or inflammatory muscle disease. The trial will last for 2487 days and involve approximately 80 participants.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive CTX112

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: To assess the pharmacodynamic response of CTX112 in adult subjects with refractory autoimmune diseases, including SLE, SSc or IIM, To assess the pharmacokinetics (PK) of CTX112 in adult subjects with refractory autoimmune diseases, including SLE, SSc or IIM

Body systems

Immune