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Study details
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A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel

Iovance Biotherapeutics, Inc.
NCT IDNCT06940739ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

42

Study length

about 7.4 years

Ages

18–70

Locations

3 sites in CO, NC, TN

What this study is about

Researchers are testing a new treatment, IOV-3001, for adults with advanced melanoma who are also receiving lifileucel. The trial will evaluate the safety and effectiveness of IOV-3001 as part of this treatment regimen.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive IOV-3001

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Safety and Tolerability

Secondary: Complete Response (CR) rate, Disease Control Rate (DCR), Duration of Response (DOR), Overall Response Rate (ORR), Overall Survival (OS), Pharmacodynamic (PD) Profile of IOV-3001, Pharmacokinetics (PK) profile of IOV-3001, Progression-Free Survival (PFS)

Body systems

Oncology