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Study details
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BXCL501 After Stress to Increase Recovery Success

University of North Carolina, Chapel Hill
NCT IDNCT06943404ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

100

Study length

about 1.1 years

Ages

18–65

Locations

3 sites in FL, MO, VA

What this study is about

This trial is testing if BXCL501 helps reduce symptoms of Acute Stress Reaction (ASR) and Acute Stress Disorder (ASD) in adults who have experienced a motor vehicle collision. Participants will receive BXCL501 or a placebo after the accident, and their symptoms, cognitive function, and any side effects will be monitored over 396 days.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take BXCL501 (dexmedetomidine HCl)
  • 2.Take Placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

dexmedetomidine, Anesthetics (Adrenergic alpha1-Agonists)

Endpoints

Secondary: Change in Depressive Symptoms Score, Change in PTSD Symptoms, Change in Pain Symptom Score, Change in Somatic Symptom Score

Body systems

Psychiatry / Mental Health