Ketamine for Opioid Use Disorder
Phase 2
50
about 3.6 years
18–65
1 site in MD
What this study is about
Researchers are testing if ketamine helps reduce opioid cravings in adults starting methadone treatment. The trial also investigates whether low doses of ketamine improve symptoms like depression and pain, and whether it leads to better treatment outcomes compared to a very low dose.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Treatment with Ketamine
- 2.Take Treatment with Very Low Dose Ketamine
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
ketamine (NMDA receptor antagonist; induces dissociative anesthesia and analgesia), anesthetic (NMDA receptor antagonist; induces dissociative anesthesia and analgesia)
Secondary: Chronic pain ratings, Insomnia Symptoms, Severity of depression symptoms, Sleep quality ratings on a Visual Analogue Scale (VAS)
Psychiatry / Mental Health