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Study details
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Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 2)

The University of Texas Health Science Center, Houston
NCT IDNCT06961916ClinicalTrials.gov data as of Apr 2026
Target enrollment

120

Study length

about 3.9 years

Ages

18–60

Locations

1 site in TX

What this study is about

This trial is testing a treatment that combines repetitive transcranial magnetic stimulation (rTMS) and cognitive training to improve brain connectivity in people with schizophrenia. The goal of it is to see if this combination can help strengthen connections between different areas of the brain, which may be disrupted in schizophrenia.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Participate in Cognitive Training
  • 2.Use Active rTMS

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Brain connectivity as indicated by resting-state functional connectivity (rsFC) values as assessed by functional MRI (fMRI), Brain microstructural integrity as indicated by white matter fractional anisotropy (FA) values as assessed by magnetic resonance imaging (MRI)

Secondary: Depression as assessed by the Beck Depression Inventory, Depression as assessed by the Calgary Depression Scale

Body systems

Psychiatry / Mental Health