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Study details
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Polygenic Risk Score Implementation and Stratification for Managing Blood Pressure

University of Alabama at Birmingham
NCT IDNCT06962488ClinicalTrials.gov data as of Apr 2026
Target enrollment

300

Study length

about 5 years

Ages

18–55

Locations

1 site in AL

What this study is about

This trial is testing whether providing a polygenic risk score (PRS) for blood pressure to people with hypertension can help them improve their health. Participants will receive either regular care or the PRS results along with counseling, and researchers will measure changes in blood pressure and other health behaviors over 12 months.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Participate in Regular Care
  • 2.Participate in SBP PRS Dissemination

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Change in Mean 24-Hour Systolic Blood Pressure

Secondary: Change in Ambulatory Blood Pressure Parameters, Change in Anxiety, Change in Body Mass Index, Change in Fat Mass, Change in Health-Related Quality of Life (CDC HRQOL-14), Change in Health-Related Quality of Life (SF-36), Change in Sleep Duration

Body systems

Cardiology / Heart