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Study details
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Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone Disease

University of Alabama at Birmingham
NCT IDNCT06989320ClinicalTrials.gov data as of Apr 2026
Target enrollment

80

Study length

about 6.6 years

Ages

18–80

Locations

2 sites in AL, TX

What this study is about

This trial is testing if people with kidney stones have increased oxalate production. Participants will follow a low-oxalate diet and take supplements to measure how much oxalate their body makes.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Low-oxalate diet and glycolate dosing
  • 2.Oral 13C- ascorbic acid dosing
  • 3.Oral glycolate dosing

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oraltopical

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

ALIMENTARY TRACT AND METABOLISM

Drug routes

oral (Oral Capsule), topical (Topical Gel)

Body systems

Renal