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Study details
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The Vanguard Study

National Cancer Institute (NCI)
NCT IDNCT06995898ClinicalTrials.gov data as of Apr 2026
Target enrollment

24,000

Study length

about 4 years

Ages

45–75

Locations

36 sites in CA, CO, HI +5

What this study is about

This trial is testing a new way to screen for cancer. It involves collecting samples, using devices, and reviewing electronic health records. The goal is to understand how well multi-cancer detection tests work as screening tools.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Electronic Health Record Review
  • 2.Questionnaire Administration
  • 3.Undergo Biospecimen Collection
  • +2 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Procedures

diagnostic

Body systems

Oncology