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Study details
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A Phase III Trial of AZD0780 on Major Adverse CV Events

AstraZeneca
NCT IDNCT07000357ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

15,100

Study length

about 4.4 years

Ages

18+

Locations

293 sites in AL, AZ, CA +38

What this study is about

Researchers are testing whether AZD0780, a medication, reduces the risk of major adverse cardiovascular events (MACE) in people who have already had heart problems or are at high risk for developing them. The trial will last 1605 days and involve approximately 15100 participants.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take AZD0780
  • 2.Take Placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Time to first event of any component of MACE-PLUS

Secondary: Time to first event of any component of 3P MACE, Time to first event of any component of MACE PLUS

Body systems

Cardiology / Heart