Study details
Enrolling now
Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures
Major Extremity Trauma Research Consortium
NCT IDNCT07006675ClinicalTrials.gov data as of Apr 2026
Phase
Phase 3
Target enrollment
1,000
Study length
about 5.8 years
Ages
18–80
Locations
13 sites in IN, MA, MD +9
What this study is about
This trial is testing whether adding NSAIDs to standard pain management improves outcomes in people with tibial shaft fractures. It compares two groups: one group receives standard pain treatment without NSAIDs, while the other group also takes NSAIDs for up to six weeks.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take 600 mg Ibuprofen
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Oral
How treatment is administered
Treatment Assignment
Randomized & Blinded
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Drug classes
ibuprofen
Drug routes
oral
Endpoints
Secondary: Persistent Pain & Pain Inference, Radiographic bone union