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Study details
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Prehabilitation With Aerobic and Resistance Exercise for Improving Physical Fitness and Quality of Life Outcomes in Older Patients Undergoing CAR-T Therapy for Relapsed or Refractory Multiple Myeloma

Mayo Clinic
NCT IDNCT07045727ClinicalTrials.gov data as of Apr 2026
Target enrollment

20

Study length

about 1.1 years

Ages

60+

Locations

1 site in MN

What this study is about

This trial is testing whether prehabilitation with aerobic and resistance exercise improves physical fitness and quality of life outcomes in older patients planning to undergo chimeric antigen receptor (CAR)-T therapy for multiple myeloma that has come back after a period of improvement (relapsed) or that does not respond to treatment (refractory). Prehabilitation programs use targeted interventions to improve functional status prior to medical treatments. In it, patients participate in personalized aerobic and resistance prehabilitation activities in the weeks leading up to their CAR-T infusion. This program may improve physical fitness and quality of life, both prior to and after CAR-T infusion, in older patients with relapsed or refractory multiple myeloma.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Aerobic Exercise
  • 2.Electronic Health Record Review
  • 3.Internet-Based Intervention
  • +3 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Change in muscle strength, Change in quality of life - EORTC QLQ-C30, Enrollment rate, Incidence of adverse events, Patient satisfaction, Retention rate

Procedures

diagnostic

Body systems

Oncology