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Study details
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A Study to Evaluate KarXT Injection

Bristol-Myers Squibb
NCT IDNCT07061288ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

48

Study length

about 2.1 years

Ages

18–55

Locations

8 sites in CA, FL, GA +3

What this study is about

Researchers are testing different doses of KarXT, a medication, to see how safe it is and what levels are reached in the body. The trial will last for about 772 days.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take KarXT

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Number of participants with adverse events (AEs), Number of participants with adverse events of special interest (AESIs), Number of participants with serious adverse events (SAEs)

Secondary: Apparent terminal phase half-life (T-HALF), Apparent total body clearance (CLT/F), Area under the plasma concentration-time curve from time zero to 672 hours (AUC(0-672)), Area under the plasma concentration-time curve from time zero to infinity (AUC(INF)), Area under the plasma concentration-time curve from time zero to time of last quantifiable concentration (AUC(0-T)), Maximum concentration (Cmax), Number of participants with AEs, Number of participants with SAEs

Body systems

Psychiatry / Mental Health