Skip to content
Study details
Enrolling now

A Study to Evaluate the Immunogenicity and Safety of mRNA-1283 COVID-19 Variant-containing Formulations

ModernaTX, Inc.
NCT IDNCT07089706ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

832

Study length

about 10 months

Ages

12+

Locations

5 sites in GA, LA, MS +1

What this study is about

This trial is testing a new type of COVID-19 vaccine called mNEXSPIKE® that contains a variant of the virus. The goal is to see how well it creates an immune response (immunogenicity) and whether it's safe for people, including adults and children.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive mRNA-1283.251 Variant-containing Formulation

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: Subprotocol 1: Part A - Number of Participants with Unsolicited Adverse Events (AEs), Serious Adverse Events (SAEs), AEs of Special Interests (AESIs), and AEs Leading to Study Withdrawal, Subprotocol 1: Part B - Number of Participants with SAEs, AESIs, and AEs Leading to Study Withdrawal, Subprotocol 1: Part B - Number of Participants with Unsolicited AEs

Body systems

Infectious