Evaluating Premedication Regimens (Methylprednisolone vs Dexamethasone-based) for the Prevention of Systemic and Injection Site Reactions to Motixafortide in Patients With Multiple Myeloma Undergoing Stem Cell Mobilization, PARADE Trial
Phase 4
94
about 1.3 years
18+
1 site in GA
What this study is about
This trial is testing whether a premedication regimen with methylprednisolone or dexamethasone helps prevent allergic reactions to motixafortide in patients with multiple myeloma undergoing stem cell mobilization. The goal is to determine which medication, methylprednisolone or dexamethasone, is better at preventing these reactions.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Electronic Health Record Review
- 2.Questionnaire Administration
- 3.Receive Recombinant Granulocyte Colony-Stimulating Factor
- +3 more
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
paracetamol (Reduces fever and pain (mechanism not fully understood)), dexamethasone, famotidine, loratadine, methylprednisolone, montelukast (Leukotriene receptor antagonist; reduces inflammation in airways), motixafortide, colony stimulating factor
oral, injection, ocular, oral (Oral Tablet), oral (Disintegrating Oral Tablet), injection (Injection), subcutaneous
Secondary: Compare Tolerability Between Regimens, Cytokine levels
diagnostic
Oncology