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Study details
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A Clinical Trial of KTX-2001 for Prostate Cancer

K36 Therapeutics, Inc.
NCT IDNCT07103018ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

144

Study length

about 2.9 years

Ages

18+

Sex

Male only

Locations

13 sites in CA, FL, MN +6

What this study is about

This trial is testing a new medication called KTX-2001 in men with advanced prostate cancer that has become resistant to other treatments. The goal is to see if the drug is safe, determine the best dose, and understand how it works in the body.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take KTX-2001
  • 2.Take KTX-2001 + Darolutamide (NUBEQA®)

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

darolutamide

Drug routes

oral (Oral Tablet)

Endpoints

Primary: Percentage of patients with dose-limiting toxicities (DLTs) to determine the maximum tolerated dose (MTD)

Secondary: Overall safety profile including adverse events, Pharmacokinetic Parameters: Maximum Observed Plasma Concentration (Cmax)

Body systems

Oncology