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Study details
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Ensuring Access to Optimal Therapy in CF: The ENACT Study

Arkansas Children's Hospital Research Institute
NCT IDNCT07148739ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

95

Study length

about 5.6 years

Ages

3+

Locations

2 sites in AR, WA

What this study is about

This trial is testing a treatment for Cystic Fibrosis (CF) that includes new drugs and genetic testing. The goal is to find out how these drugs work, who will respond well, and avoid unnecessary side effects or expensive treatments.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Elexacaftor / Ivacaftor / Tezacaftor
  • 2.Use therapeutic drug monitoring

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

Respiratory System Agent (Cytochrome P450 1A2 Inhibitors), ivacaftor

Drug routes

oral (Oral Tablet)

Body systems

Respiratory