Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, OFS Trial
Phase 2
75
about 2 years
18+
Female only
1 site in MI
What this study is about
This trial is testing whether leuprolide or goserelin can help lower estrogen production from the ovaries in women with breast cancer who are pre- or peri-menopausal. Estrogen can fuel the growth of some breast cancer cells. It compares different doses of leuprolide and goserelin to see which one best suppresses ovarian function and reduces estrogen levels.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Electronic Health Record Review
- 2.Questionnaire Administration
- 3.Take Goserelin
- +2 more
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You are randomly assigned, but you will know your treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
goserelin, leuprorelin (GnRH agonist; suppresses testosterone (and estrogen) production after initial surge)
Secondary: Change in FACT-ES Endocrine Symptom Subscale, Incidence of adverse events (AEs)
diagnostic