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Study details
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A Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Rilvegostomig in Adult Participants With Advanced Solid Tumors Previously Treated With Standard of Care Therapy

AstraZeneca
NCT IDNCT07161414ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

40

Study length

about 3.7 years

Ages

18+

Locations

3 sites in NC, TX, VA

What this study is about

This trial is testing a subcutaneous (SC) dose of rilvegostomig. The goal is to determine if this SC dose provides similar exposure levels to the intravenous (IV) form, and to evaluate its safety in adults with advanced solid tumors who have already received standard cancer treatments.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive IV Rilvegostomig
  • 2.Take Recombinant Human Hyaluronidase (rHu)
  • 3.Take SC Rilvegostomig
  • +1 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVInjection / IV

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

Enzyme Replacements/Modifiers (Enzyme Interactions)

Drug routes

infusion, injection (Injection)

Endpoints

Secondary: Number of participants with adverse events (AEs)