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Study details
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A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of TJ101 in Patients With Advanced/Metastatic Solid Tumors

Phrontline Biopharma
NCT IDNCT07181473ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

200

Study length

about 2.1 years

Ages

18+

Locations

3 sites in FL, TN, TX

What this study is about

This trial is testing a treatment called TJ101 for people with advanced solid tumors. The goal is to see if it's safe and effective. Participants will receive TJ101 through IV infusions, have their tumor images checked regularly, provide blood samples, and be monitored for side effects.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take TJ101

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug routes

intravenous

Endpoints

Primary: Number of participants with Serious Adverse Events (SAEs), Number of participants with treatment-emergent adverse events (TEAEs), Number of participants with treatment-related adverse events (TRAEs)

Secondary: Area under the concentration versus time curve (AUC), Clearance (CL), Disease control rate (DCR), Duration of response (DoR), Maximum observed concentration (Cmax), Objective response rate (ORR), Overall survival (OS), Progression-free survival (PFS)

Body systems

Oncology