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Study details
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HIV-1 Virologic Suppression With TMB-365 and TMB-380 Antibodies Trial

TaiMed Biologics Inc.
NCT IDNCT07215468ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

75

Study length

about 1.7 years

Ages

18+

Locations

10 sites in CA, FL, NV +2

What this study is about

This trial is testing whether a combination of antibodies, TMB-365 and TMB-380, can maintain viral suppression in people with HIV who are no longer taking oral medications. Participants will receive either an infusion of the antibodies every 8 weeks or continue daily oral medication for 48 weeks. Researchers will compare these two approaches to see which one is more effective at keeping the virus under control.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Baseline ART
  • 2.Take TMB-365
  • 3.Take TMB-380

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVOral

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug routes

intravenous, oral

Endpoints

Secondary: Pharmacokinetic profile of TMB-365, Pharmacokinetic profile of TMB-380

Body systems

Immune, Infectious