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Study details
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REGULUS Trial

Stanford University
NCT IDNCT07223307ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

62

Study length

about 4.1 years

Ages

18+

Locations

1 site in CA

What this study is about

This trial is testing a new way to deliver radiation therapy called MRI-guided adaptive SABR. It uses imaging scans to plan and adjust the treatment during one session for patients with liver cancers.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive MRI-guided adaptive stereotactic ablative body radiotherapy (SABR)

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: 1-year Overall Survival (OS)

Secondary: Change from Baseline in COST-FACIT Total Score up to 1 Year Post-SABR, Change from Baseline in EORTC QLQ-C30 Global Health Status/Quality of Life Score up to 1 Year Post-SABR, Change from Baseline in FACT-Hep Total Score up to 1 Year Post-SABR, Rate of Grade ≥ 2 Chest Wall Toxicity, Rate of Grade ≥ 2 Gastrointestinal (GI) Adverse Events

Procedures

radiation

Body systems

Gastroenterology