Study details
Enrolling now
BIGSHOT Trial
Medical University of South Carolina
NCT IDNCT07227610ClinicalTrials.gov data as of Apr 2026
Phase
Phase 2
Target enrollment
54
Study length
about 3 years
Ages
18+
Locations
1 site in SC
What this study is about
This trial is testing whether staged stereotactic radiosurgery (SSRS) or fractionated stereotactic radiotherapy (FSRT) is better for treating large brain metastases. The goal is to compare the effectiveness and safety of these two radiation treatments.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Receive Fractionated Stereotactic Radiotherapy (FSRT)
- 2.Receive Staged Stereotactic Radiosurgery (SSRS)
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Standard
How treatment is administered
Treatment Assignment
Randomized (Open Label)
You are randomly assigned, but you will know your treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Endpoints
Secondary: Compare the safety profile by radiation toxicity
Procedures
radiation
Body systems
Oncology